American Society for Clinical Pathology Board of Certification (ASCP BOC); historical CLSp(MB) issuer: National Credentialing Agency for Laboratory Personnel (NCA) · ASCP BOC MB Examination Content Guideline, revised December 5, 2025; no separate effective date stated. Reviewed for the user-facing date October 13, 2026, Asia/Hong_Kong. The assigned workbook label identifies the historical NCA CLSp(MB) credential. The original AMP certification working-group report documents its transition to MB(ASCP) following the 2009 NCA–ASCP unification. The current official examination title is Scientist in Molecular Biology. The assigned slug is preserved; these materials use the current MB outline, not a historical CLSp(MB) outline.

This original 20-question sample covers selected topics across the outline. It does not reproduce official exam questions or cover every tested topic.

• Scientist in Molecular Biology — MB(ASCP) and MB(ASCPi): Examination Content Guideline
• Technologist in Molecular Biology: Examination Content Guideline, September 25, 2025
• ASCP Board of Certification History, 1994–2018
• Certification — Association for Molecular Pathology
• Certification in Molecular Pathology in the United States: An Update from the AMP Training and Education Committee
• Talking Glossary of Genetic Terms — NHGRI
• Alternative Splicing — NHGRI
• DNA Ligation — New England Biolabs
• Reverse Transcription (cDNA Synthesis) — New England Biolabs
• Efficiency of Real-Time PCR — Thermo Fisher Scientific
• Applied Biosystems 7500/7500 Fast Real-Time PCR System: Standard Curve Experiments
• Analysis of DNA Methylation by Bisulfite Conversion — New England Biolabs
• What Is Sanger Sequencing? — Thermo Fisher Scientific
• DNA Gel Electrophoresis — Thermo Fisher Scientific
• Sequencing Quality Scores — Illumina
• Restriction Fragment Length Polymorphism — NHGRI
• Good Laboratory Practices for Molecular Genetic Testing for Heritable Diseases and Conditions
• Definition of c-ABL — National Cancer Institute
• Huntington's Disease — MedlinePlus Genetics
• Prader-Willi Syndrome — MedlinePlus Genetics
• Clinical Testing and Diagnosis for C. diff Infection — CDC
• CPIC Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update
• Evaluation of STR Informativity for Chimerism Testing
• Transplant Solutions — Promega